Soojin V. Yi

The paper shows that peri/centromeric regions in ape genomes are hypomethylated CpG reservoirs, linking germline hypomethylation to CpG evolution and structural transcriptomic innovation.

This study identifies CCNB1IP1 as a regulator of neocortex size and folding in primates, showing its expression increased alongside brain evolution.

The paper presents a draft genome assembly of Carpobrotus chilensis, revealing low heterozygosity, high transposable element content, and low sequence divergence from its invasive relative C. edulis.

The paper quantifies marker fidelity and background expression of cortical cell types using single-nucleus transcriptomics data and extends canonical markers with improved subtype-specific markers.

The paper profiles genomic and methylome data in California mussels to show promoter methylation repression and age-linked CpGs, linking methylation to gene regulation and aging.

The paper maps DNA-embedded ribonucleotides (rNMPs) across human cell types, revealing their non-random distribution and role as a novel epigenetic mark affecting gene expression.

This study examines how duplication affects enhancer evolution, finding duplicated enhancers are longer, more pleiotropic, and associated with immune functions and stress responses.

This study identifies age-related DNA methylation changes in neurons and oligodendrocytes, showing that epigenetic drift is a stronger predictor of methylation variation than sex or disease.

The paper presents whole-genome DNA methylomes of tree shrew brains, revealing conserved and divergent DNA methylation patterns on sex chromosomes compared to other mammals.

The paper produces gapless assemblies of ape sex chromosomes for five great apes and a lesser ape, revealing divergence in Y chromosomes and evolutionary dynamics.

The paper examines DNA methylation differences between female and male X chromosomes in human brain cells using whole genome bisulfite sequencing, revealing global hypomethylation on female X chromosomes and promoter-specific hypermethylation.

This study shows that knocking down Dnmt1 in Nasonia disrupts gene body methylation, leading to gene expression changes and developmental failure during the maternal-zygotic transition.

The paper shows DNA methylation changes linked to development and chromosomal suppression of recombination in white-throated sparrows, with implications for genome integrity and gene expression.

The paper shows that a single gene within a supergene contributes to aggressive behavior in white-throated sparrows through allelic imbalance and regulatory variation.

The paper investigates DNA methylation evolution in human brain cells, showing reduced CG methylation and increased CH methylation, linked to schizophrenia risk.

The paper analyzes cell-type specific DNA methylation and transcriptomes in schizophrenia brains, finding reduced epigenetic distinction between cell types in schizophrenia.