Author

Matthew C. Pahl

Children's Hospital of PhiladelphiaORCID 0000-0003-2969-6024Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genomics· 2 Developmental Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:differential expression· 2 Research Focus:gene regulatory network inference· 2 Organism:human· 2 Approach:statistical model· 2 Assay:ATAC-seq· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1

Frequent Co-Authors

Alessandra ChesiiD· 2 shared Andrew D. WellsiD· 2 shared James A. PippiniD· 2 shared Struan F.A. GrantiD· 2 shared Alex C. KeeneiD· 1 shared Allan I PackiD· 1 shared Amber J. ZimmermaniD· 1 shared Babette S. ZemeliD· 1 shared

Activity by Year

2023-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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2 shared papersGenomics

Alessandra ChesiORCID

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3 papers

Recent·Most cited

GenomicsGenome biologyPeer-reviewedOct 3, 2025

GWAS-informed data integration and non-coding CRISPRi screen illuminate genetic etiology of bone mineral density

Mitchell Conery, James A. Pippin, Yadav Wagley…·Struan F.A. Grant

The paper integrates GWAS data with a CRISPRi screen in osteoblasts to identify genes affecting bone mineral density and reveals pleiotropy across non-bone tissues.

6 citations

humanGWAS summary statistics

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GenomicsbioRxivPreprintAug 17, 2023

Perturbation of the insomnia WDR90 GWAS locus pinpoints rs3752495 as a causal variant influencing distal expression of neighboring gene, PIG-Q

Shilpa Sonti, Sheridan H. Littleton, Matthew C. Pahl…·Struan F.A. Grant

This study identifies rs3752495 as the causal variant at the insomnia WDR90 GWAS locus that influences PIG-Q expression through a regulatory mechanism.

1 citation

humanATAC-seq

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Developmental BiologybioRxivPreprintMar 28, 2023

Delta-dependent Notch activation closes the early neuroblast temporal program to promote lineage progression and neurogenesis termination in Drosophila

Chhavi Sood, Md Ausrafuggaman Nahid, Kendall R. Branham…·Sarah E Siegrist

The paper identifies Delta-dependent Notch activation as a mechanism that terminates neuroblast temporal programs and promotes lineage progression in Drosophila.

DOI 10.1101/2023.03.28.534626

Drosophilaexperimental assay

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