Amber J. Zimmerman

This study identifies DPYD's role in sleep regulation through glial lipid metabolism and myelination across species, linking genetic variants to oligodendrocyte-specific control.

The paper identifies MEIS1 as a gene involved in sleep abnormalities and cerebellar development using cross-species variant-to-function analyses in zebrafish.

The paper identifies EGR2 as a conserved sleep regulator by analyzing sub-threshold genetic signals across sleep-related traits in multiple species.

The paper identifies cell-type-specific genes regulating sleep by mapping GWAS variants to effector genes in human and Drosophila models, revealing ruby/AP3B2 as a conserved glial regulator.

The paper identifies beat-Ia/CADM2 as a gene involved in hypersomnia by showing its role in sleep regulation across species and demonstrates potential therapeutic targets.

This study shows that knocking out NSG2 enhances associative learning and cognitive flexibility without affecting motor or affective behaviors.

This study identifies rs3752495 as the causal variant at the insomnia WDR90 GWAS locus that influences PIG-Q expression through a regulatory mechanism.

The paper identifies GPI-anchor biosynthesis as a conserved regulator of sleep through variant-to-gene mapping and cross-species genetic screening in humans and model organisms.

The paper identifies conserved genes at insomnia GWAS loci using zebrafish CRISPR screens and chromatin interaction data, finding that MEIS1 and SKIV2L mutations produce insomnia-like behaviors.