Irina Sousa Moreira

This study identifies hnRNP H2's role in neuronal development and shows how disease variants disrupt its function, leading to neurodevelopmental defects.

The paper identifies sex-dependent differences in placental vascular development, showing increased angiogenic activity in male placentas early in gestation and reduced sex differences at term.

This study shows that a stargazin mutation causes cognitive and synaptic defects in mice, linking it to intellectual disability.

This study shows Rac1 in microglia is crucial for synaptic proteome plasticity and cognitive performance through homeostatic regulation and synapse communication.

The paper evaluates HADDOCK's performance in CAPRI rounds 38-45, showing it produces acceptable or better models for most targets using data-driven strategies.

This study uses computational modeling to investigate how anti-HER2 antibodies affect HER2 dimerization by analyzing conformational changes in key regions of the receptor.