Ana Magalhães

Meningeal γδ T cells facilitate bacterial entry into the brain in neonatal meningitis and trigger long-term behavioural sequelae

This study shows that meningeal γδ17 T cells promote bacterial entry into the brain during neonatal meningitis and cause long-term behavioral issues.

Give It Time: Green Anacondas Show Prolonged Behavioral Responses to Enclosure Enhancements

This study evaluates how enclosure enhancements affect green anacondas' behavior over time, finding increased activity and space use after modifications, even when habituation was expected.

Cofilin pathology is a new player on α-synuclein-induced spine impairment in models of hippocampal synucleinopathy

This study identifies cofilin dysregulation as a mediator of α-synuclein-induced synaptic dysfunction in hippocampal neurons in synucleinopathy models.

Prefrontal cortex proteomic alteration after social instability stress in adolescents rats

This study examines how social instability stress during adolescence affects prefrontal cortex proteomics in rats, revealing sex- and age-dependent molecular changes.

Rac1 signaling in microglia is essential for synaptic proteome plasticity and experience-dependent cognitive performance

This study shows Rac1 in microglia is crucial for synaptic proteome plasticity and cognitive performance through homeostatic regulation and synapse communication.

Astrocyte-derived TNF and glutamate critically modulate microglia reactivity by methamphetamine

This study shows that Meth exposure causes microglia reactivity through astrocyte-derived TNF and glutamate, affecting behavior in adult mice.

Altered environmental perception by parental stress and depression vulnerability: impact on mothers and offspring

The paper investigates how maternal stress affects maternal behavior and offspring cognition in rats with different depression vulnerability, finding differential impacts on oxytocin levels and cognitive outcomes.

Alcohol intake triggers aberrant synaptic pruning leading to synapse loss and anxiety-like behavior

This study shows that alcohol intake causes excessive synaptic pruning by microglia, leading to synapse loss and anxiety-like behavior.

Microglia dysfunction caused by the loss of Rhoa disrupts neuronal physiology and leads to neurodegeneration

This study shows that loss of Rhoa in microglia causes neurodegeneration through Src-mediated Tnf production and excitotoxic glutamate secretion.