Benoît Coste

The paper creates a detailed computational model of rat somatosensory cortex anatomy, including 4.2 million neurons and 14.2 billion synapses, and identifies limitations in connectivity prediction from morphology.

The paper develops a computational model of mouse thalamoreticular microcircuitry to study sensory enhancement and sleep spindle properties, revealing mechanisms of network-level activity across brain states.

The paper synthesizes cortical dendrites using a topological descriptor to create statistically similar digital reconstructions, enabling the study of neuronal morphology and brain function.

The paper digitally reconstructs the neuro-glia-vascular system in rat somatosensory cortex to understand astrocyte-vascular-neuron interactions and their anatomical constraints.