Author

Douglas R. Keene

Shriners Hospitals for Children - PortlandORCID 0000-0003-2986-370XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Developmental Biology· 3 Genetics· 1

Signature Assays, Organisms & Methods

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Organism:mouse· 4 Approach:experimental assay· 3 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:statistical model· 1 Organism:zebrafish· 1

Frequent Co-Authors

Sara F. TufaiD· 3 shared David M. HudsoniD· 2 shared Marilyn Archer· 2 shared Amel DudakoviciD· 1 shared André J. van WijneniD· 1 shared Bashar HasaniD· 1 shared Brendan LeeiD· 1 shared Catherine Glauber AmbroseiD· 1 shared

Activity by Year

2020-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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3 shared papersDevelopmental Biology

Sara F. TufaORCID

Mutual co-authors in cluster

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4 papers

Recent·Most cited

Developmental BiologyMatrix BiologyPeer-reviewedSep 1, 2022

Vertebrate extracellular matrix protein hemicentin-1 interacts physically and genetically with basement membrane protein nidogen-2

Jin-Li Zhang, Stefânia Konrad Richetti, Thomas Ramezani…·Matthias Hammerschmidt

This study identifies nidogen-2 as a physical and genetic interaction partner of hemicentin-1, showing their cooperative role in basement membrane integrity.

22 citations

mousezebrafish

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GeneticseLifePeer-reviewedMay 26, 2021

Tendon and Motor Phenotypes in the Crtap-/- Mouse Model of Recessive Osteogenesis Imperfecta

Matthew William Grol, Nele A.T Haelterman, Joohyun Lim…·Brendan Lee

This study examines tendon and motor phenotypes in Crtap-/- mice, finding thinner tendons, altered collagen structure, and motor impairments linked to tendon/ligament dysfunction in OI.

20 citations

mousebulk RNA-seq

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Developmental BiologyScientific ReportsPeer-reviewedMay 25, 2021

Rcn3 is Involved in Postnatal Tendon Development by Regulating Collagen Modification and Fibrillogenesis

Na Rae Park, Snehal S. Shetye, Igor Bogush…·Kyu Sang Joeng

This study shows that Rcn3 regulates collagen modification and fibrillogenesis in postnatal tendon development, affecting tendon structure and mechanical properties.

22 citations

mouseexperimental assay

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Developmental BiologybioRxivPreprintOct 30, 2020

Enhancer of Zeste Homolog 2 (Ezh2) is essential for patterning of multiple musculoskeletal tissues but dispensable for tendon differentiation

Deepanwita Pal, Scott M. Riester, Bashar Hasan…·Ronen Schweitzer

This study investigates the role of Ezh2 in musculoskeletal development, showing it is essential for patterning muscles and skeleton but not required for tendon differentiation.

DOI 10.1101/2020.10.30.361949

mouseexperimental assay

𝕏 PostBluesky