Author

André J. van Wijnen

Mayo ClinicORCID 0000-0002-4458-0946Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Developmental Biology· 2 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:chromatin & epigenetic regulation· 1 Organism:human· 1 Approach:statistical model· 1

Frequent Co-Authors

Amel DudakoviciD· 2 shared Abigail G. Person· 1 shared Alquassem Abuorquob· 1 shared Andrew J. FritziD· 1 shared Bashar HasaniD· 1 shared Cong GaoiD· 1 shared Deepanwita PaliD· 1 shared Deli HongiD· 1 shared

Activity by Year

2020-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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2 shared papersDevelopmental Biology

Amel DudakovicORCID

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Author profile →

3 papers

Recent·Most cited

Acute degron-mediated RUNX1 loss reprograms enhancer activity to epigenetically drive epithelial destabilization and initiate cancer hallmarks

Andrew J. Fritz, Haley W. Greenyer, Louis Dillac, Priyanka Chavarkar, Rahim Ullah, Miles Malik, Deli Hong, Rabail Hassan Toor, Emory Pacht, Abigail G. Person, Georgiy Zotkin, Sadie J Korzec, Cong Gao, Alquassem Abuorquob, Janine S. A. Warren, , Gary S. Stein

This study shows that acute RUNX1 loss reprograms enhancer activity, leading to epithelial destabilization and cancer hallmark activation in human mammary epithelial cells.

bioRxiv · Mar 28, 2026 · PreprintCancer Biology

Enhancer of Zeste Homolog 2 (Ezh2) is essential for patterning of multiple musculoskeletal tissues but dispensable for tendon differentiation

Deepanwita Pal, Scott M. Riester, Bashar Hasan, Sara F. Tufa, Amel Dudakovic, Douglas R. Keene, André J. van Wijnen, Ronen Schweitzer

This study investigates the role of Ezh2 in musculoskeletal development, showing it is essential for patterning muscles and skeleton but not required for tendon differentiation.

bioRxiv · Oct 30, 2020 · PreprintDevelopmental Biology

Modifiers and Mediators of Craniosynostosis Severity Revealed by Differential Gene Expression

Amel Dudakovic, Hwa Kyung Nam, André J. van Wijnen, Nan E. Hatch

The paper compares gene expression in two mouse models of craniosynostosis to identify genetic modifiers affecting disease severity.

bioRxiv · Jan 28, 2020 · PreprintDevelopmental Biology