Matthias Hammerschmidt

Exploring mechanisms of scar-free skin wound healing in adult zebrafish in comparison to mouse

The paper compares scar-free skin wound healing in zebrafish and mice, identifying differences in fibroblast behavior and collagen crosslinking mechanisms.

Vertebrate extracellular matrix protein hemicentin-1 interacts physically and genetically with basement membrane protein nidogen-2

This study identifies nidogen-2 as a physical and genetic interaction partner of hemicentin-1, showing their cooperative role in basement membrane integrity.

Incoherent collective cell chemotaxis underlies organ dysmorphia in a model of branchio-oto-renal syndrome

This study shows that loss of Eya1 disrupts CXCR7b expression, leading to abnormal collective cell chemotaxis and organ dysmorphia in a zebrafish model of branchio-oto-renal syndrome.

TGS1 controls snRNA 3' end processing, prevents neurodegeneration and ameliorates SMN-dependent neurological phenotypes in vivo

This study shows TGS1 is essential for snRNA 3' end processing and its loss causes neurodegeneration, which can be mitigated by human TGS1 expression in model organisms.

The Vertebrate Codex Gene Breaking Protein Trap Library For Genomic Discovery and Disease Modeling Applications

The paper describes a zebrafish gene break transposon library for genomic discovery and disease modeling, identifying novel gene expression patterns and generating models for human disease loci.