GeneticsThe American Journal of Human GeneticsPeer-reviewed
A dementia-associated risk variant near TMEM106B alters chromatin architecture and gene expression
Michael D. Gallagher, Marijan Posavi, Peng Huang…·Alice S. Chen‐Plotkin
The paper identifies a causal variant near TMEM106B that alters chromatin architecture and gene expression, linking it to frontotemporal lobar degeneration and neurodegenerative disease risk.
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