Author

Susan Elizabeth Lester

Queen Elizabeth HospitalORCID 0000-0003-3013-2701Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Assay:proteomics· 1

Frequent Co-Authors

Eugene RoscioliiD· 2 shared Hubertus P. A. JersmanniD· 2 shared Shiye Chen· 2 shared Anton BlencoweiD· 1 shared Arash BadieiiD· 1 shared Benjamin T. KoppiD· 1 shared Emily LawtoniD· 1 shared James M Cooper· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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2 shared papersMolecular Biology

Eugene RoscioliORCID

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2 papers

Recent·Most cited

Molecular BiologyInternational Journal of Molecular SciencesPeer-reviewedJun 13, 2026

Autophagy is suppressed in peripheral blood mononuclear cells during chronic obstructive pulmonary disease.

James M Cooper, Shiye Chen, Susan Elizabeth Lester…·Eugene Roscioli

The paper shows that autophagy is suppressed in peripheral blood mononuclear cells of COPD patients, as indicated by reduced autophagic flux and fewer autophagy-related vacuoles.

1 citation

humanbulk RNA-seq

𝕏 PostBluesky

BiochemistrybioRxivPreprintApr 25, 2024

Modifying Azithromycin to Mitigate Arrested Autophagy

Ryan D. Quarrington, Shiye Chen, Sylvia A. Sapula…·Eugene Roscioli

This paper shows azithromycin inhibits autophagy and presents a modified version, AZM-[O], that reduces this effect while retaining antimicrobial and immunomodulatory functions.

1 citation

humanproteomics

𝕏 PostBluesky