Cancer BiologybioRxivPreprint
Hepatocyte expression of fetal insulin receptor isoform contributes to the promotion of liver cancer through non-cell autonomous mechanisms
Fanny Léandre, Akila Iddir, Cécile Godard…·Christèle Desbois‐Mouthon
This study shows that hepatocyte expression of fetal insulin receptor isoform INSR-A promotes liver cancer through non-cell autonomous mechanisms by increasing inflammation and enabling preneoplastic cell proliferation.
DOI 10.1101/2025.06.02.655477