Michael Troup

This study evaluates five de novo mutation calling tools on real and simulated whole genome sequencing trio data, finding low concordance and tool-specific performance.

This study identifies maternal iron deficiency as an environmental teratogen causing congenital heart disease in mice, with potential implications for human health.

Scavenger recovers unaligned RNA-seq reads using aligned reads' information, improving gene expression analysis and revealing pseudogene expression impacts.

CIDR improves clustering accuracy for scRNA-Seq data by using implicit imputation and dimensionality reduction, outperforming existing methods like t-SNE and ZIFA.

Falco accelerates and reduces the cost of scRNA-seq analysis by parallelizing pipelines on cloud infrastructure.