Dorota Szumska

The paper shows that maternal diabetes and Nkx2-5 haploinsufficiency together cause severe cardiac defects in mice, with single-cell multiomic data revealing transcriptional and chromatin changes.

This study investigates how hypoxia affects coronary vessel formation during heart development by analyzing gene expression and regulatory pathways in genetically modified mice.

This paper identifies FSS-dependent enhancers for KLF2 and reveals an essential MEF2-TBP double motif in their regulation, demonstrating a specific mechanism for FSS-induced gene activation.

The paper identifies a primed endothelial progenitor that requires VEGF/ERK inhibition to differentiate into vein endothelial cells, revealing a two-step process for vein development.

The paper identifies molecular markers for placental arterial and venous endothelial cells and shows maternal iron deficiency impairs the arterial vascular network.

This study identifies maternal iron deficiency as an environmental teratogen causing congenital heart disease in mice, with potential implications for human health.