Author

Masayoshi Nagai

University of MichiganORCID 0000-0003-3025-037XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:ChIP-seq· 2 Approach:experimental assay· 2 Organism:human· 2 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Robert S. PorteriD· 2 shared Shigeki IwaseiD· 2 shared Aijia Wang· 1 shared Benoît LaurentiD· 1 shared Bo O. ZhouiD· 1 shared Cecilia M Gavilan· 1 shared Elizabeth D. Hughes· 1 shared Jacqueline I. KimiD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersMolecular Biology

Robert S. PorterORCID

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2 papers

Recent·Most cited

Molecular BiologyCell ReportsPeer-reviewedJan 1, 2025

A neuron-specific microexon ablates the novel DNA-binding function of a histone H3K4me0 reader PHF21A

Robert S. Porter, Sojin An, María Cecilia Gavilán…·Shigeki Iwase

The paper identifies neuron-specific microexon splicing in chromatin regulators, showing that PHF21A loses DNA-binding function in neurons while retaining H3K4me0 recognition, contributing to brain development.

8 citations

humanChIP-seq

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BiochemistryJournal of Biological ChemistryPeer-reviewedOct 10, 2024

Asynchronous microexon splicing of LSD1 and PHF21A during neurodevelopment

Masayoshi Nagai, Robert S. Porter, Maxwell Miyasato…·Shigeki Iwase

The paper shows that PHF21A microexon expression precedes LSD1 microexon expression during neurodevelopment, leading to stepwise deactivation of the LSD1-PHF21A complex and unique gene-regulatory roles in neurons.

8 citations

humanmouse

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