Sarah Perin Otto

This study shows that evolutionary rescue in toxic metal combinations depends on metal interactions, with antagonistic combinations leading to broader fitness benefits than synergistic ones.

This study investigates pleiotropy in host defense mechanisms of C. elegans against Pseudomonas aeruginosa by analyzing gene knockouts and their effects on multiple defense traits.

The paper models how recombination-associated mutation affects the evolution of recombination rates, finding that mutation near crossovers reduces the advantage of recombination.

This study shows that increased sexual selection in yeast leads to rapid evolutionary changes in mating traits and sexual differentiation.

The paper evaluates how well phylogenetic tip rate methods predict future diversification using fossil and extant tetrapod data, finding moderate success with some methods.

The paper analyzes changes in the status of imperiled species in British Columbia from 2008 to 2024, finding that most status changes were non-genuine due to methodological updates rather than true population or threat changes.

The paper develops a model that integrates energy and ribosomal allocation to predict trait costs under varying environmental conditions and genetic backgrounds.

The paper quantifies metal interaction effects on yeast growth using two metrics, finding nonadditive toxicity patterns linked to redox properties and gene overlap.

This study investigates cross-tolerance to metals in yeast by evolving lines to single metals and testing their tolerance to others, finding unpredictable patterns and genetic bases.

The paper examines how nongenetic variation in vital rates affects population growth and evolvability by modifying age-structured population models to include individual heterogeneity.

The paper derives fixation probabilities for alleles in a haploid-diploid population with asexual reproduction, showing how reproductive values and ecological differences influence evolutionary dynamics.

The paper examines genetic variation in Pacific oyster populations across the Northern Hemisphere, identifying genetic differentiation and selection signatures linked to translocation history and aquaculture practices.