Developmental BiologyDevelopmentPeer-reviewed
A novel self-organizing embryonic stem cell system reveals signaling logic underlying the patterning of human ectoderm
George Britton, Idse Heemskerk, Rachel A. Hodge…·Aryeh Warmflash
This paper develops an in vitro model of human ectodermal patterning using hESCs that self-organize into patterns mimicking the dorsal-ventral axis, revealing the role of WNT and BMP signaling in fate decisions.
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