Author

George Britton

Rice UniversityORCID 0000-0002-2783-4801Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Research Focus:trajectory inference· 1

Frequent Co-Authors

Aryeh WarmflashiD· 2 shared Aimal H. Khankhel· 1 shared Amina Ann QutubiD· 1 shared Boris I. ShraimaniD· 1 shared Eric D. SiggiaiD· 1 shared Eyal KarzbruniD· 1 shared Heitor C. Megale· 1 shared Idse HeemskerkiD· 1 shared

Activity by Year

2019-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersDevelopmental Biology

Aryeh WarmflashORCID

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2 papers

Recent·Most cited

Self-organized morphogenesis of a human neural tube in vitro by geometric constraints

Eyal Karzbrun, Aimal H. Khankhel, Heitor C. Megale, Stella M.K. Glasauer, Yofiel Wyle, George Britton, Aryeh Warmflash, Kenneth S. Kosik, Eric D. Siggia, Boris I. Shraiman, Sebastian J. Streichan

This paper describes an in vitro method to self-organize a human neural tube using geometric constraints, showing that neural and epidermal tissues are sufficient for morphogenesis.

Nature · Oct 27, 2021Peer-reviewedDevelopmental Biology

A novel self-organizing embryonic stem cell system reveals signaling logic underlying the patterning of human ectoderm

George Britton, Idse Heemskerk, Rachel A. Hodge, Amina Ann Qutub, Aryeh Warmflash

This paper develops an in vitro model of human ectodermal patterning using hESCs that self-organize into patterns mimicking the dorsal-ventral axis, revealing the role of WNT and BMP signaling in fate decisions.

Development · Jan 1, 2019Peer-reviewedDevelopmental Biology