Author

Isaac J. Villegas

University of California Davis Medical CenterORCID 0000-0003-3047-2116Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Cell Biology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Assay:electrophysiology· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

Julian A. N. M. HalmaiiD· 2 shared Kyle D. FinkiD· 2 shared Adriana Portillo· 1 shared Cyrrus M. EspinoiD· 1 shared Kyle Shang· 1 shared Mandar M. Patil· 1 shared Mandeep Singh· 1 shared Nadya J BerberiD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersNeuroscience

Julian A. N. M. HalmaiORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

NeurosciencebioRxivPreprintMay 29, 2026

Intersectional CRISPR-Cas9 genetic targeting reveals acute role of Nav1.1 in proprioceptive behavior and function

Cyrrus M. Espino, Isaac J. Villegas, Serena Ortiz…·Theanne N. Griffith

This study uses an intersectional CRISPR-Cas9 approach to target NaV1.1 in proprioceptors, revealing its essential role in motor coordination and action potential firing.

DOI 10.64898/2026.05.26.727016

mouseexperimental assay

𝕏 PostBluesky

Cell BiologybioRxivPreprintMay 27, 2026

Cortical Organoid Model of PPP2R5D Genetic Intellectual Disability Models Disease Severity Phenotype

Yuxin Du, Mandeep Singh, Mandar M. Patil…·Kyle D. Fink

This study uses cortical organoids to model PPP2R5D mutations in Jordans Syndrome, identifying gene expression, protein, and electrophysiological changes linked to disease severity.

DOI 10.64898/2026.05.26.728012

humanbulk RNA-seq

𝕏 PostBluesky