Author

Xunde Xian

Peking UniversityORCID 0000-0003-3059-1254Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Joachim HerziD· 2 shared Alon Rabinovich· 1 shared Alondra Schweizer BurgueteiD· 1 shared Andrey A. BobkoviD· 1 shared Annie LeeiD· 1 shared Badri Narayan VardarajaniD· 1 shared Beatrice Acheson· 1 shared Bret M. EversiD· 1 shared

Activity by Year

2021-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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2 shared papersNeuroscience

Joachim HerzORCID

Mutual co-authors in cluster

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2 papers

Recent·Most cited

NeuroscienceDOAJ (DOAJ: Directory of Open Access Journals)Peer-reviewedJul 1, 2026

CD33 and Clusterin Interact Biophysically and Genetically to Modulate Alzheimer Risk

Roger B. Dodd, Masahiro Enomoto, Ye Zhou…·Peter St George‐Hyslop

This study shows how non-coding variants in CD33 affect Alzheimer's risk by altering CD33M dimerization and interactions with clusterin and Aβ, impacting microglial function.

1 citationtop 5%

humanproteomics

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NeuroscienceeLifePeer-reviewedOct 7, 2021

NHE6-Depletion Corrects ApoE4-Mediated Synaptic Impairments and Reduces Amyloid Plaque Load

Theresa Pohlkamp, Xunde Xian, Connie Hau Yan Wong…·Joachim Herz

This study shows that NHE6 inhibition corrects ApoE4-mediated synaptic impairments and reduces amyloid plaque load, suggesting a potential therapeutic strategy for Alzheimer's disease.

45 citations

humanexperimental assay

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