Cancer BiologyClinical and Translational MedicinePeer-reviewed
Loss-of-Function genetic Screen Unveils Synergistic Efficacy of PARG Inhibition with Combined 5-Fluorouracil and Irinotecan Treatment in Colorectal Cancer
Cristina Queralt, Cristina Moreta-Moraleda, Marta Costa…·Eva Martinez‐Balibrea
This study identifies PARG as a therapeutic target in colorectal cancer, showing that its inhibition synergizes with 5FU and irinotecan to improve treatment efficacy.
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