Cristina Moreta-Moraleda

The paper identifies high piRNA abundance as a key feature of evolutionarily persistent piRNA-producing loci across mouse and primate species.

This study identifies PARG as a therapeutic target in colorectal cancer, showing that its inhibition synergizes with 5FU and irinotecan to improve treatment efficacy.

This paper shows PARP1 regulates 3D chromatin structure and gene expression at super-enhancers and hormone-control regions in breast cancer cells through chromatin looping and compartment organization.

The paper analyzes piRNA expression variation across mouse strains and finds genetic differences contribute to strain-specific piRNA production, including from retrovirus insertions and protein-coding genes.