Eva Musulén

Spatial transcriptomics unveils the in situ cellular and molecular hallmarks of the lung in fatal COVID-19

This study uses spatial transcriptomics to analyze lung tissue from fatal COVID-19 cases, identifying cellular and molecular changes during disease progression.

A pan-cancer single-cell atlas of pericytes

The paper constructs a pan-cancer single-cell RNA sequencing atlas of pericytes, revealing a common transcriptional program in tumour-associated pericytes and their specialised subtypes across multiple cancers.

Discovery and evaluation of novel biomarkers reveal dasatinib as a potential treatment for a specific subtype of Triple-Negative Breast Cancer

This study identifies BC-markers in TNBC, links them to poor prognosis and dasatinib sensitivity, suggesting TAGLN as a predictive biomarker for targeted therapy.

Loss-of-Function genetic Screen Unveils Synergistic Efficacy of PARG Inhibition with Combined 5-Fluorouracil and Irinotecan Treatment in Colorectal Cancer

This study identifies PARG as a therapeutic target in colorectal cancer, showing that its inhibition synergizes with 5FU and irinotecan to improve treatment efficacy.

Benchmarking of spatial transcriptomics platforms across six cancer types

This study benchmarks spatial transcriptomics and proteomics platforms across six cancer types, identifying platform-specific strengths and limitations in data quality and biological insights.