Gary J. Gorbsky

This study identifies a critical segment in SKA3's C-terminus that mediates interaction between SKA and NDC80 complexes, essential for metaphase-to-anaphase transition in mitosis.

This paper challenges the conventional view of trisomy 12 origin in iPSCs by showing it arises de novo in diploid cells through anaphase bridging and micronuclei formation, leading to rapid dominance of trisomic cells.

This paper identifies AAV serotypes effective for transducing amphibian CNS cells and develops tools for neural circuit tracing and manipulation in multiple amphibian species.

The paper shows that yeast cells with elevated chromosome numbers are dependent on Mps1 for proper chromosome orientation during mitosis, revealing a mechanism for Mps1 addiction in aneuploid cells.