Author
Rutgers, The State University of New JerseyORCID 0000-0003-3085-1618Unclaimed ORCID profile · follow to get notified of new preprints
3 papers
Recent·Most cited
N Li, RL Myers, Qin Zhu…·Christopher J. Lengner
This study identifies that APC loss in colorectal cancer drives a β-CATENIN-independent fetal intestinal transcriptional program through YAP activation, leading to bistable stem cell states and enhanced tumorigenesis.
Oscar Pellón-Cárdenas, P Rout, S Hassan…·MP Verzi
The paper shows Pdgfra+ fibroblasts reprogram during WNT-driven oncogenesis to promote a regenerative state in the epithelium, facilitating tumor formation.
Charlie J. Childs, Emily M. Holloway, Caden W. Sweet…·Jason R. Spence
The paper identifies EPIREGULIN as a niche factor that enables spatial organization in human intestinal organoids, mimicking the native intestine's structure and gene expression.