Author

Joerg Huelsken

École Polytechnique Fédérale de LausanneORCID 0000-0003-3105-9606Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:clustering· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1

Frequent Co-Authors

Antonia DigkliaiD· 1 shared Brinda BalasubramanianiD· 1 shared Carmen PiniD· 1 shared Christophe CisarovskyiD· 1 shared Gordon William MoraniD· 1 shared Jonathan BaciD· 1 shared Krisztián HomicskóiD· 1 shared Louis GalliD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperCancer Biology

Antonia DigkliaORCID

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2 papers

Recent·Most cited

Cancer BiologybioRxivPreprintFeb 13, 2026

Deciphering spatial heterogeneity of patient-derived organoids of colorectal tumors for drug discovery

Maxim N. Norkin, Jonathan Bac, Louis McConnell…·Krisztián Homicskó

This study develops a platform to analyze spatial heterogeneity in colorectal tumor organoids using spatial transcriptomics and validates it against single-cell and tumor spatial data.

DOI 10.64898/2026.02.10.704651

humanspatial transcriptomics

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Molecular BiologyStem Cell Research & TherapyPeer-reviewedDec 21, 2025

Intestinal Stem and Progenitor Cells Exhibit Distinct Adaptive Responses to Inflammatory Stress in IBD

Brinda Balasubramanian, Shivam Patel, Louis Gall…·Paloma Ordóñez‐Morán

The paper examines how intestinal stem and progenitor cells respond to inflammation in IBD, finding distinct transcriptional changes and new immune-responsive cell states.

7 citationstop 5%

humanbulk RNA-seq

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