Author

Sofia Rossini

Max Planck SocietyPrimary ORCID profile (0000-0001-6429-9425 · 1 paper)Unclaimed ORCID profile · follow to get notified of new preprints

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Same name, identified by ORCID

Sofia RossiniiD1 paper · University of Perugia

Biology Disciplines

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Cancer Biology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:proteomics· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:host-pathogen & immune response· 1 Research Focus:protein design· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

Andreas MetousisiD· 1 shared Antonio MacchiaruloiD· 1 shared Barbara A. SteigenbergeriD· 1 shared Charlotte Duteil· 1 shared Ciriana OrabonaiD· 1 shared Claudia VolpiiD· 1 shared Eleonora PanfiliiD· 1 shared Elisa BianconiiD· 1 shared

Activity by Year

2023-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperCancer Biology

Andreas MetousisORCID

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2 papers

Recent·Most cited

Spatial proteomics reveals mechanisms of cell-intrinsic tryptophan metabolism controlling ovarian cancer survival

Teng Teng Xu, Andreas Metousis, Lisa Kainacher, Xin Zhang, Barbara A. Steigenberger, Katherine G. Madden, Laura Schweitzer, Charlotte Duteil, Sofia Rossini, Ernst R. Lengyel, Eva Obermayr, Ziv Shulman, Thierry M. Nordmann, Eric L. Lindberg, Matthias Mann, Peter J. Murray

The paper uses spatial proteomics to show IDO1's tumor-suppressive role in ovarian cancer by linking it to tryptophan metabolism and stress response pathways.

bioRxiv · Aug 14, 2025 · PreprintCancer Biology

A Back-Door Insights into the modulation of Src kinase activity by the polyamine spermidine

Sofia Rossini, Marco Gargaro, Giulia Scalisi, Elisa Bianconi, Sara Ambrosino, Eleonora Panfili, Claudia Volpi, Ciriana Orabona, Antonio Macchiarulo, Francesca Fallarino, Giada Mondanelli

This study identifies spermidine as a positive allosteric modulator of Src kinase by binding to a novel site on the SH2 domain, enhancing its interaction with IDO1.

eLife · Jun 30, 2023Peer-reviewedMolecular Biology