Author

Susan L. Cotman

Harvard UniversityORCID 0000-0003-3114-0543Unclaimed ORCID profile · follow to get notified of new preprints

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Neuroscience· 1

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Approach:experimental assay· 1 Organism:mouse· 1

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Alessio Vittorio ColomboiD· 1 shared Elisabeth S. ButziD· 1 shared Janos GrohiD· 1 shared Luca Montore· 1 shared Matthias PresteliD· 1 shared Sabina TahirovićiD· 1 shared Sarah K. TschirneriD· 1 shared Seda YaşaiD· 1 shared

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Recent·Most cited

NeuroscienceCommunications BiologyPeer-reviewedOct 22, 2024

Loss of CLN3 in microglia leads to impaired lipid metabolism and myelin turnover

Seda Yaşa, Elisabeth S. Butz, Alessio Vittorio Colombo…·Susan L. Cotman

This study shows that loss of CLN3 in microglia causes lipid metabolism defects and impaired myelin turnover, leading to early neuroinflammation in a mouse model of CLN3 disease.

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mouseexperimental assay

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