Elisabeth S. Butz

This study shows that loss of CLN3 in microglia causes lipid metabolism defects and impaired myelin turnover, leading to early neuroinflammation in a mouse model of CLN3 disease.

This study shows that a DSG2 mutation causing Dsg2 truncation leads to a lethal intestinal barrier defect and a skewed IL17 response in mice, similar to Crohn's disease.

This study investigates how voltage-gated sodium channels shape the light responses of mouse retinal ganglion cells, showing that specific channel properties determine contrast selectivity and response transience.