Seda Yaşa

This study shows that phosphorylation of Rab7A at serine 72 modulates its palmitoylation and retromer recruitment, with NEK7 as the kinase responsible for this phosphorylation.

This study shows that loss of CLN3 in microglia causes lipid metabolism defects and impaired myelin turnover, leading to early neuroinflammation in a mouse model of CLN3 disease.

This study shows that CLN3 deficiency disrupts stress granule dynamics and translation, linking it to neurodegenerative disease mechanisms.