Sébastien Gauvrit

This study shows that PITX2C deficiency leads to reduced oxidative metabolism and increased oxidative stress in atrial myocytes, causing arrhythmogenic remodeling and structural changes, which can be mitigated by antioxidants.

This study identifies Hhex as a regulator of hepatopancreatic ductal system specification and growth in zebrafish, showing its role in progenitor specification and interaction with blood vessels and the yolk syncytial layer.