Chiara Villa

The paper develops a model to show phenotypic adaptation drives drug resistance in BRAFV600E-mutant melanoma and suggests intermittent treatments may be more effective.

This paper develops a stochastic model to assess the identifiability of phenotypic adaptation parameters from low-cell-count experiments and shows that cell-to-cell heterogeneity is non-identifiable from population-level data.

This study examines how two rounds of whole genome duplication in vertebrates shaped human gene regulatory networks, showing increased complexity and redundancy from WGD events.