Locus-specific spatial and transcriptional dynamics direct T cell lineage choice in the thymus
Ilinca Patrascan, James W. D. King, Noura Maziak…·Matthias Merkenschlager
The paper investigates how spatial and transcriptional dynamics at Cd4 and Cd8 loci influence T cell lineage choice in the thymus, revealing locus-specific chromatin environments that drive differentiation.