Author

Wouter W. Wiegant

Leiden University Medical CenterORCID 0000-0003-3137-6433Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 2 Genomics· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 3 Research Focus:gene regulatory network inference· 3 Organism:human· 3 Assay:DNA methylation· 2 Approach:experimental assay· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1

Frequent Co-Authors

Haico van AttikumiD· 3 shared Magdalena B. Rother· 2 shared Matthias AltmeyeriD· 2 shared Alexander van OudenaardeniD· 1 shared Alfred C.O. VertegaaliD· 1 shared Bert van de KooijiD· 1 shared Brian A. JoughiniD· 1 shared Brooke L. LatouriD· 1 shared

Activity by Year

2020-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 26 mutual co-author links

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3 shared papersMolecular Biology

Haico van AttikumORCID

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3 papers

Recent·Most cited

GenomicsbioRxivPreprintAug 22, 2025

THE NSL COMPLEX PROMOTES NEURAL DEVELOPMENT BY PREVENTING R-LOOP INDUCED REPLICATION STRESS

Jolanthe Lingeman, Diana van den Heuvel, Jeroen van den Berg…·Haico van Attikum

This study shows the NSL complex prevents R-loop induced replication stress during neural development, leading to developmental abnormalities when disrupted.

DOI 10.1101/2025.08.22.671281

humanbulk RNA-seq

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Molecular BiologyNature CommunicationsPeer-reviewedAug 16, 2024

The Fanconi anemia core complex promotes CtIP-dependent end-resection to drive homologous recombination at DNA double-strand breaks

Bert van de Kooij, Fenna J. van der Wal, Magdalena B. Rother…·Haico van Attikum

This study identifies FANCL and Ube2T as HR-promoting factors at DSBs and shows they regulate CtIP recruitment and end-resection for homologous recombination.

30 citationstop 4%

humanDNA methylation

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Molecular BiologyNucleic Acids ResearchPeer-reviewedMar 27, 2020

PHF2 regulates homology-directed DNA repair by controlling the resection of DNA double strand breaks

Ignacio Alonso‐de Vega, Maria Cristina Paz‐Cabrera, Magdalena B. Rother…·Veronique A. J. Smits

33 citations

humanDNA methylation

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