Author

Daniela Anne Braun

Boston Children's HospitalORCID 0000-0003-3146-1566Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Assay:CRISPR screen· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Research Focus:perturbation response prediction· 1 Research Focus:variant calling· 1

Frequent Co-Authors

Amar J. MajmundariD· 1 shared Amber K. O’ConnoriD· 1 shared Anja Stegemann· 1 shared Birte SeegeriD· 1 shared Boris V. SkryabiniD· 1 shared Chaozhe YangiD· 1 shared Friedhelm HildebrandtiD· 1 shared Hanan FathyiD· 1 shared

Activity by Year

2021-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperMolecular Biology

Amar J. MajmundarORCID

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2 papers

Recent·Most cited

Molecular BiologyiSciencePeer-reviewedOct 21, 2025

CRISPR-Cas9 HDR Optimization: RAD52, Denatured and 5'-Modified DNA Templates in Knock-In Mice Generation

Boris V. Skryabin, Daniela Anne Braun, Helena Kaiser…·Timofey S. Rozhdestvensky

This study identifies strategies to improve CRISPR-Cas9 HDR efficiency in generating conditional knockout mice by optimizing DNA templates and using RAD52 protein.

2 citations

mouseCRISPR screen

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Molecular BiologyScientific ReportsPeer-reviewedSep 14, 2021

Cystin gene mutations cause autosomal recessive polycystic kidney disease associated with altered Myc expression

Chaozhe Yang, Naoe Harafuji, Amber K. O’Connor…·Lisa M. Guay‐Woodford

This paper shows that Cys1 gene mutations cause ARPKD by altering Myc expression, using mouse models and a human patient case.

22 citations

mousehuman

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