NeurosciencebioRxivPreprint
POMC-specific knockdown of Tril reduces body adiposity and increases hypothalamic leptin responsiveness
Alexandre Moura‐Assis, Pedro A. S. Nogueira, José Carlos de Lima Júnior…·Licio Augusto Velloso
The paper identifies Tril as a mediator of high-fat diet effects in POMC neurons, showing that its knockdown reduces adiposity and increases leptin responsiveness in the hypothalamus.
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