Qingguo Xu

Liposomal DAGLβ Inhibitor Shows Substantial Antinociceptive Potency Mediated by AMPK in a Neuropathic Pain Mouse Models

The paper demonstrates that liposomal DAGLβ inhibitor KT109 shows significantly higher antinociceptive potency in neuropathic pain models, mediated by AMPK activation.

Machine Learning Guided Optimization of an Oral Microemulsion System: A Bayesian Optimization Approach

This study uses Bayesian optimization to design stable oral microemulsions, identifying high-performing formulations with improved drug loading and stability.

Nitric Oxide-Releasing Thixotropic Hydrogels as Antibacterial and Hemocompatible Catheter Locks

This paper introduces a nitric oxide-releasing hydrogel catheter lock that prevents bacterial contamination and improves hemocompatibility.

Nor-LAAM loaded PLGA Microparticles for Treating Opioid Use Disorder

This paper develops sustained-release nor-LAAM-loaded PLGA microparticles for OUD treatment, showing prolonged drug release and reduced fentanyl choice and withdrawal in rats.