Author

Madeline Gunawardena

Virginia Commonwealth UniversityORCID 0009-0007-9279-0896Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioengineering· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:Bayesian inference· 1 Approach:experimental assay· 1 Organism:mouse· 1

Frequent Co-Authors

Qingguo XuiD· 2 shared Rudra PangeniiD· 2 shared Aron H. LichtmaniD· 1 shared Bao ChauiD· 1 shared Charles J. McGilliD· 1 shared Dayna A Adeso· 1 shared Hayden Nothacker· 1 shared Ku‐Lung HsuiD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersPharmacology & Toxicology

Qingguo XuORCID

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2 papers

Recent·Most cited

Pharmacology & ToxicologybioRxivPreprintOct 21, 2026

Liposomal DAGLβ Inhibitor Shows Substantial Antinociceptive Potency Mediated by AMPK in a Neuropathic Pain Mouse Models

Liam Babcock, Madeline Gunawardena, Payton E. Lowrey…·Aron H. Lichtman

The paper demonstrates that liposomal DAGLβ inhibitor KT109 shows significantly higher antinociceptive potency in neuropathic pain models, mediated by AMPK activation.

DOI 10.64898/2026.10.15.758837

mouseexperimental assay

𝕏 PostBluesky

BioengineeringAAPS OpenPeer-reviewedJul 2, 2026

Machine Learning Guided Optimization of an Oral Microemulsion System: A Bayesian Optimization Approach

Madeline Gunawardena, Bao Chau, Hayden Nothacker…·Charles J. McGill

This study uses Bayesian optimization to design stable oral microemulsions, identifying high-performing formulations with improved drug loading and stability.

DOI 10.1186/s41120-026-00176-0

Bayesian inferencedrug response / drug discovery

𝕏 PostBluesky