Author
The University of Texas at AustinORCID 0009-0000-1352-4477Unclaimed ORCID profile · follow to get notified of new preprints
4 papers
Recent·Most cited
Liam Babcock, Madeline Gunawardena, Payton E. Lowrey…·Aron H. Lichtman
The paper demonstrates that liposomal DAGLβ inhibitor KT109 shows significantly higher antinociceptive potency in neuropathic pain models, mediated by AMPK activation.
Claire C. Weckerly, Olivia L. Murtagh, Tiernan Swayhoover…·Gerald R. V. Hammond
The paper investigates paralog-specific effects of DGK inhibitors on PA generation during PLC signaling in live cells, finding that BMS-502 inhibits PA production while R59022 paradoxically increases it.
Zhihong Li, Hsiao-Kuei Tsai, Adam H. Libby…·Ku‐Lung Hsu
The paper develops a chemoproteomics platform to map the human purine interactome and identifies a regioselective ligand for ACAT2 with potential therapeutic applications in cancer.
Minhaj Shaikh, Surya Pravo Mookherjee, Claire C. Weckerly…·Ku-Lung Hsu
This study identifies a stereoselective DGK inhibitor that enhances T cell activation and tumor cell cytotoxicity through proteasome-dependent degradation of DGK.