Author

Matthew W. Mahoney

Washington University in St. LouisORCID 0000-0003-3191-2128Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Microbiology· 2

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Organism:mouse· 1

Frequent Co-Authors

Adrianus C. M. BooniD· 2 shared James W. JanetkaiD· 2 shared Traci L. BrickeriD· 2 shared Brigid V. TroaniD· 1 shared Carolina Alisio· 1 shared Elizabeth A. Weiland· 1 shared Ethan J. FritchiD· 1 shared Kendra L. GullyiD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersMicrobiology

Adrianus C. M. BoonORCID

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2 papers

Recent·Most cited

MicrobiologyEuropean Journal of Medicinal ChemistryPeer-reviewedNov 21, 2025

Inhibitors of membrane associated serine proteases block replication of coronavirus SARS-CoV-2 and influenza virus H1N1

Victoria S. Banas, Kuljeet Seehra, Matthew W. Mahoney…·James W. Janetka

The paper develops and tests new inhibitors of TMPRSS2 to block replication of SARS-CoV-2 and H1N1 influenza virus.

4 citations

experimental assaydrug response / drug discovery

𝕏 PostBluesky

MicrobiologyJournal of VirologyPeer-reviewedApr 9, 2024

Efficacy of Host Cell Serine Protease Inhibitor MM3122 against SARS-CoV-2 for Treatment and Prevention of COVID-19

Adrianus C. M. Boon, Traci L. Bricker, Ethan J. Fritch…·James W. Janetka

This paper demonstrates that MM3122, a host cell serine protease inhibitor, effectively inhibits SARS-CoV-2 replication and reduces disease severity in mice, both prophylactically and therapeutically.

19 citationstop 3%

mouseexperimental assay

𝕏 PostBluesky