Author
Washington University in St. LouisORCID 0000-0002-9888-5411Unclaimed ORCID profile · follow to get notified of new preprints
3 papers
Recent·Most cited
Victoria S. Banas, Kuljeet Seehra, Matthew W. Mahoney…·James W. Janetka
The paper develops and tests new inhibitors of TMPRSS2 to block replication of SARS-CoV-2 and H1N1 influenza virus.
Zijian Guo, Victoria S. Banas, Yuanyuan He…·Michael D. Vahey
The paper shows ciliated airway cells activate influenza HA more efficiently than non-ciliated cells, and HA activation occurs intracellularly in the Golgi, affecting antiviral protease inhibitor efficacy.
Adrianus C. M. Boon, Traci L. Bricker, Ethan J. Fritch…·James W. Janetka
This paper demonstrates that MM3122, a host cell serine protease inhibitor, effectively inhibits SARS-CoV-2 replication and reduces disease severity in mice, both prophylactically and therapeutically.