Author

Caroline E. Kratka

Northwestern UniversityORCID 0000-0003-3225-5545Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Research Focus:cell type annotation· 3 Research Focus:cell-cell communication· 2 Research Focus:differential expression· 2 Organism:mouse· 2 Assay:scRNA-seq· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Approach:experimental assay· 1

Frequent Co-Authors

Brittany A. GoodsiD· 3 shared Francesca E. DuncaniD· 3 shared Ruixu HuangiD· 3 shared Jeffrey PeaiD· 2 shared Achla H. Gandhi· 1 shared Alex K. ShalekiD· 1 shared Anthony J. DayiD· 1 shared Audrey M Olmsted· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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3 shared papersBioinformatics

Brittany A. GoodsORCID

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3 papers

Recent·Most cited

Cell BiologybioRxivPreprintJul 23, 2026

Proprotein convertase activity regulates cumulus-oocyte-complex matrix integrity and cumulus cell migration during ovulation via a GDF9-dependent mechanism

Caroline E. Kratka, Ruixu Huang, Jeffrey Pea…·Francesca E. Duncan

This study identifies PCSK5A and GDF9 as key regulators of cumulus-oocyte-complex matrix integrity and cumulus cell migration during late ovulation, with implications for fertility therapeutics.

DOI 10.64898/2026.07.22.738304

mousebulk RNA-seq

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BioinformaticsPLoS BiologyPeer-reviewedJun 24, 2025

Single-cell and spatiotemporal profile of ovulation in the mouse ovary

Ruixu Huang, Caroline E. Kratka, Jeffrey Pea…·Brittany A. Goods

This study maps the spatiotemporal profile of ovulation in mice using single-cell RNA-seq and spatial transcriptomics, identifying cell state markers and interactions involved in the process.

22 citationstop 1%

mousescRNA-seq

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BioinformaticsbioRxivPreprintJun 20, 2025

A single-cell atlas inclusive of age-related menopause reveals global tissue and ovarian remodeling

Hannah M. VanBenschoten, Zhanel Nugmanova, Audrey M Olmsted…·Brittany A. Goods

The paper presents MenoMap, a single-cell atlas of 2 million cells from 13 tissues including the ovary, analyzing gene expression changes across pre- and post-menopausal donors.

DOI 10.1101/2025.06.20.660779

humanscRNA-seq

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