Richard Cheng-An Chang

This study shows that ancestral tributyltin exposure impairs male brown adipose thermogenic function, leading to increased fat accumulation and reduced mitochondrial capacity after high-fat diet.

This study shows cold exposure increases energy expenditure and limits weight gain in both lean and obese mice, regardless of diet.

The paper presents a joint genomic analysis of UDN patients using whole genome sequencing and new statistical methods to prioritize disease genes, revealing new disease associations and releasing a software tool for cohort analysis.

This study shows that exposure to the obesogen tributyltin causes heritable changes in chromatin structure in germ cells, leading to transgenerational obesity in male offspring.

The paper identifies miR-223 as a key regulator of TBT-induced adipogenesis in MSCs and its transgenerational role in obesity.