Bruce Blumberg

This study shows that ancestral tributyltin exposure impairs male brown adipose thermogenic function, leading to increased fat accumulation and reduced mitochondrial capacity after high-fat diet.

This study shows cold exposure increases energy expenditure and limits weight gain in both lean and obese mice, regardless of diet.

The paper shows that the structural similarity index from CHESS is unreliable due to noise in Hi-C data, warning against its biological interpretation.

This study shows that exposure to the obesogen tributyltin causes heritable changes in chromatin structure in germ cells, leading to transgenerational obesity in male offspring.

The paper identifies miR-223 as a key regulator of TBT-induced adipogenesis in MSCs and its transgenerational role in obesity.

The paper shows that ancestral exposure to the obesogen tributyltin in mice leads to transgenerational obesity in unexposed F4 male descendants through heritable changes in genome architecture.