Author

Ana Polache

Universitat de ValènciaORCID 0000-0003-3237-6574Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:rat· 2 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Organism:mouse· 1 Assay:multiome· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Lucía HipólitoiD· 3 shared Yolanda Campos‐JuradoiD· 3 shared Jesús David LorenteiD· 2 shared Luis M. GraneroiD· 2 shared Ana MeleroiD· 1 shared Antonio José GuillotiD· 1 shared Javier CuitaviiD· 1 shared Jessica A. HigginbothamiD· 1 shared

Activity by Year

2019-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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3 shared papersNeuroscience

Lucía HipólitoORCID

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3 papers

Recent·Most cited

Development and pharmacological evaluation of an intranasal liposomal norbinaltorphimine formulation for the prevention of pain-induced negative affect

Jesús David Lorente, Yolanda Campos‐Jurado, Miquel Martínez‐Navarrete, Javier Cuitavi, Marta Cervera-Sospedra, Jessica A. Higginbotham, Ana Melero, Ana Polache, Antonio José Guillot, Jose Moron, Lucía Hipólito

This paper develops an intranasal liposomal NorBNI formulation that selectively delivers KOR antagonists to the brain, reducing systemic exposure and off-target effects while improving pain-induced negative affect.

bioRxiv · Sep 1, 2026 · PreprintNeuroscience

Dose-Dependent Induction Of CPP Or CPA By Intra-pVTA Ethanol: Role Of Mu Opioid Receptors And Effects On NMDA Receptors

Yolanda Campos‐Jurado, Lucía Martí‐Prats, José A. Morón, Ana Polache, Luis M. Granero, Lucía Hipólito

This study shows ethanol induces CPP or CPA via intra-VTA administration, with dose-dependent effects and MOR involvement, and alters NMDA receptor subunit expression in NAc and Hippocampus.

Progress in Neuro-Psychopharmacology and Biological Psychiatry · Jan 21, 2020Peer-reviewedNeuroscience

Effect Of Inflammatory Pain On Alcohol-Induced Dopamine Release In The Nucleus Accumbens: Behavioural Implications In Rat Models.

Yolanda Campos‐Jurado, Jesús David Lorente, José Luis González-Romero, Luis M. Granero, Ana Polache, Lucía Hipólito

This study investigates how inflammatory pain affects alcohol-induced dopamine release and behavior in rats, showing reduced dopamine response and altered place preference.

bioRxiv · Dec 2, 2019 · PreprintNeuroscience