Cristina Puchades

This study determines the structure of AFG3L2, revealing how its unique features influence enzymatic activity and disease-related mutations.

The paper determines the cryo-EM structure of Y. pestis Lon protease during substrate processing, revealing a distinct hand-over-hand translocation mechanism unique to the HCLR clade.

The paper presents the first atomic structure of the mitochondrial inner membrane AAA+ protease YME1, revealing its mechanism of substrate processing and translocation.