Albert S. Song

This study reports the cryo-EM structure of DELE1's C-terminal fragment, showing its oligomerization and role in activating the integrated stress response.

The paper determines the cryo-EM structure of yeast Lon protease (PIM1) and shows it forms a hexamer similar to bacterial and human Lon proteases, with unique structural features and a dispensable yeast-specific insertion.

This study determines the cryo-EM structures of human LONP1 to elucidate the molecular mechanism of its proteolytic activation and regulation.

This study determines the structure of AFG3L2, revealing how its unique features influence enzymatic activity and disease-related mutations.