Genetic & Genomic MedicineCommunications MedicinePeer-reviewed
Carriers of LRRK2 pathogenic variants show a milder, anatomically distinct brain signature of Parkinsons disease
Jakub Kopál, Andrew Vo, Qin Tao…·Alain Dagher
This study examines how LRRK2 pathogenic variants affect brain structure in Parkinson's disease patients and non-manifesting carriers, finding milder cortical atrophy in LRRK2 PD patients and no atrophy in carriers.