Author
Heidelberg UniversityORCID 0000-0003-3264-6028Unclaimed ORCID profile · follow to get notified of new preprints
4 papers
Recent·Most cited
Blue B. Lake, Ricardo Melo Ferreira, Jens Hansen…·Sanjay R. Jain
The paper presents a multi-modal atlas of human kidney disease, identifying cellular and spatial mechanisms of injury resolution or failure and linking them to clinical outcomes.
Dylan Lawless, Pauline Rogg, Manon Bouzereau…·Luregn Jan Schlapbach
The paper identifies genetic pathways and variants associated with sepsis susceptibility in children through genomic analysis of a paediatric cohort.
Aurélien J. F. Dugourd, Pascal Lafrenz, Diego Mañanes…·Julio Sáez-Rodríguez
The paper introduces COSMOS+ to integrate mechanistic prior knowledge with multi-omics data analysis to generate mechanistic hypotheses about disease resistance mechanisms.
Sophia Müller‐Dott, Eirini Tsirvouli, Miguél Vázquez…·Julio Sáez-Rodríguez
CollecTRI-derived signed regulons, spanning 1,183 transcription factors (TFs) and 45,856 TF-gene links, outperform DoRothEA, ChEA3, RegNetwork and Pathway Commons at identifying perturbed TFs in KnockTF data.