A pathogenic role for histone H3 copper reductase activity in a yeast model of Friedreich's Ataxia
Oscar A. Campos, Narsis Attar, Chen Cheng…·Siavash K. Kurdistani
The paper shows that reducing histone H3-mediated Cu1+ production restores Fe-S cluster deficiencies in yeast, linking chromatin and mitochondrial function to Fe-S cluster homeostasis.